Covalent linking of photoreactive gonadotropin-releasing hormone to gonadotropes produces a prolonged signal.

A bioactive, photoreactive derivative of gonadotropin-releasing hormone (GnRH; gonadoliberin), [azidobenzoyl-D-Lys6]GnRH, was shown to bind covalently to dispersed pituitary cells after irradiation. Approximately 7% of the total cell-associated radioactivity was covalently bound to the receptors. Ph...

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Veröffentlicht in:	Proc Natl Acad Sci U S A
Hauptverfasser:	Hazum, E, Keinan, D
Format:	Artigo
Sprache:	Inglês
Veröffentlicht:	National Academy of Sciences 1983
Schlagworte:	Research Article
Online-Zugang:	https://ncbi.nlm.nih.govhttps://pmc.ncbi.nlm.nih.gov/articles/PMC393718/ https://ncbi.nlm.nih.govhttps://pubmed.ncbi.nlm.nih.gov/6300878/ https://ncbi.nlm.nih.govhttps://doi.org/10.1073/pnas.80.7.1902
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