Covalent linking of photoreactive gonadotropin-releasing hormone to gonadotropes produces a prolonged signal.
A bioactive, photoreactive derivative of gonadotropin-releasing hormone (GnRH; gonadoliberin), [azidobenzoyl-D-Lys6]GnRH, was shown to bind covalently to dispersed pituitary cells after irradiation. Approximately 7% of the total cell-associated radioactivity was covalently bound to the receptors. Ph...
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| Publicado en: | Proc Natl Acad Sci U S A |
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| Autores principales: | , |
| Formato: | Artigo |
| Lenguaje: | Inglês |
| Publicado: |
National Academy of Sciences
1983
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| Materias: | |
| Acceso en línea: | https://ncbi.nlm.nih.govhttps://pmc.ncbi.nlm.nih.gov/articles/PMC393718/ https://ncbi.nlm.nih.govhttps://pubmed.ncbi.nlm.nih.gov/6300878/ https://ncbi.nlm.nih.govhttps://doi.org/10.1073/pnas.80.7.1902 |
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