β-alanine suppresses malignant breast epithelial cell aggressiveness through alterations in metabolism and cellular acidity in vitro

BACKGROUND: Deregulated energetics is a property of most cancer cells. This phenomenon, known as the Warburg Effect or aerobic glycolysis, is characterized by increased glucose uptake, lactate export and extracellular acidification, even in the presence of oxygen. β-alanine is a non-essential amino...

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Detalhes bibliográficos
Main Authors: Vaughan, Roger A, Gannon, Nicholas P, Garcia-Smith, Randi, Licon-Munoz, Yamhilette, Barberena, Miguel A, Bisoffi, Marco, Trujillo, Kristina A
Formato: Artigo
Idioma:Inglês
Publicado em: BioMed Central 2014
Assuntos:
Research
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC3937146/
https://ncbi.nlm.nih.gov/pubmed/24460609
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1186/1476-4598-13-14
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