Effects of Caffeine on Metabolism and Mitochondria Biogenesis in Rhabdomyosarcoma Cells Compared with 2,4-Dinitrophenol

PURPOSE: This work investigated if treatment with caffeine or 2,4-dinitrophenol (DNP) induce expression of peroxisome proliferator-activated receptor coactivator 1 alpha (PGC-1α) and increase both mitochondrial biosynthesis and metabolism in skeletal muscle. METHODS: Human rhabdomyosarcoma cells wer...

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Detalhes bibliográficos
Main Authors: Vaughan, Roger A., Garcia-Smith, Randi, Bisoffi, Marco, Trujillo, Kristina A., Conn, Carole A.
Formato: Artigo
Idioma:Inglês
Publicado em: Libertas Academica 2012
Assuntos:
Original Research
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC3698477/
https://ncbi.nlm.nih.gov/pubmed/23882149
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.4137/NMI.S10233
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