Identification of Novel Genetic Loci Associated with Thyroid Peroxidase Antibodies and Clinical Thyroid Disease

Autoimmune thyroid diseases (AITD) are common, affecting 2-5% of the general population. Individuals with positive thyroid peroxidase antibodies (TPOAbs) have an increased risk of autoimmune hypothyroidism (Hashimoto's thyroiditis), as well as autoimmune hyperthyroidism (Graves' disease)....

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Hlavní autoři: Medici, Marco, Porcu, Eleonora, Pistis, Giorgio, Teumer, Alexander, Brown, Suzanne J., Jensen, Richard A., Rawal, Rajesh, Roef, Greet L., Plantinga, Theo S., Vermeulen, Sita H., Lahti, Jari, Simmonds, Matthew J., Husemoen, Lise Lotte N., Freathy, Rachel M., Shields, Beverley M., Pietzner, Diana, Nagy, Rebecca, Broer, Linda, Chaker, Layal, Korevaar, Tim I. M., Plia, Maria Grazia, Sala, Cinzia, Völker, Uwe, Richards, J. Brent, Sweep, Fred C., Gieger, Christian, Corre, Tanguy, Kajantie, Eero, Thuesen, Betina, Taes, Youri E., Visser, W. Edward, Hattersley, Andrew T., Kratzsch, Jürgen, Hamilton, Alexander, Li, Wei, Homuth, Georg, Lobina, Monia, Mariotti, Stefano, Soranzo, Nicole, Cocca, Massimiliano, Nauck, Matthias, Spielhagen, Christin, Ross, Alec, Arnold, Alice, van de Bunt, Martijn, Liyanarachchi, Sandya, Heier, Margit, Grabe, Hans Jörgen, Masciullo, Corrado, Galesloot, Tessel E., Lim, Ee M., Reischl, Eva, Leedman, Peter J., Lai, Sandra, Delitala, Alessandro, Bremner, Alexandra P., Philips, David I. W., Beilby, John P., Mulas, Antonella, Vocale, Matteo, Abecasis, Goncalo, Forsen, Tom, James, Alan, Widen, Elisabeth, Hui, Jennie, Prokisch, Holger, Rietzschel, Ernst E., Palotie, Aarno, Feddema, Peter, Fletcher, Stephen J., Schramm, Katharina, Rotter, Jerome I., Kluttig, Alexander, Radke, Dörte, Traglia, Michela, Surdulescu, Gabriela L., He, Huiling, Franklyn, Jayne A., Tiller, Daniel, Vaidya, Bijay, de Meyer, Tim, Jørgensen, Torben, Eriksson, Johan G., O'Leary, Peter C., Wichmann, Eric, Hermus, Ad R., Psaty, Bruce M., Ittermann, Till, Hofman, Albert, Bosi, Emanuele, Schlessinger, David, Wallaschofski, Henri, Pirastu, Nicola, Aulchenko, Yurii S., de la Chapelle, Albert, Netea-Maier, Romana T., Gough, Stephen C. L., Meyer zu Schwabedissen, Henriette, Frayling, Timothy M., Kaufman, Jean-Marc, Linneberg, Allan, Räikkönen, Katri, Smit, Johannes W. A., Kiemeney, Lambertus A., Rivadeneira, Fernando, Uitterlinden, André G., Walsh, John P., Meisinger, Christa, den Heijer, Martin, Visser, Theo J., Spector, Timothy D., Wilson, Scott G., Völzke, Henry, Cappola, Anne, Toniolo, Daniela, Sanna, Serena, Naitza, Silvia, Peeters, Robin P.
Médium: Artigo
Jazyk:Inglês
Vydáno: Public Library of Science 2014
Témata:
Research Article
On-line přístup:https://ncbi.nlm.nih.gov/pmc/articles/PMC3937134/
https://ncbi.nlm.nih.gov/pubmed/24586183
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1371/journal.pgen.1004123
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