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Learning Gene Networks under SNP Perturbations Using eQTL Datasets

The standard approach for identifying gene networks is based on experimental perturbations of gene regulatory systems such as gene knock-out experiments, followed by a genome-wide profiling of differential gene expressions. However, this approach is significantly limited in that it is not possible t...

Ausführliche Beschreibung

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Bibliographische Detailangaben
Hauptverfasser: Zhang, Lingxue, Kim, Seyoung
Format: Artigo
Sprache:Inglês
Veröffentlicht: Public Library of Science 2014
Schlagworte:
Online Zugang:https://ncbi.nlm.nih.gov/pmc/articles/PMC3937098/
https://ncbi.nlm.nih.gov/pubmed/24586125
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1371/journal.pcbi.1003420
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