Letter to the Editor regarding: Epistatic effects in pathophysiology of asthma and the “missing heritability” of this disease: Re: Yoshikawa T, Kanazawa H, Fujimoto S, Hirata K.: Epistatic effects of multiple receptor genes on pathophysiology of asthma – its limits and potential for clinical application. Med Sci Monit, 2014, 20: 64–71

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