Llwytho...

Sildenafil enhances locomotor activity in young mice and exerts anxiogenic effects in both young and aged mice

BACKGROUND: Sildenafil is a selective PDE5 inhibitor that increases cGMP levels in the target tissues and is an effective treatment agent for erectile dysfunction. The nitric oxide-cGMP pathway might be implicated in regulation of certain CNS functions, including locomotor activity and anxiety. MATE...

Disgrifiad llawn

Wedi'i Gadw mewn:
Manylion Llyfryddiaeth
Prif Awduron: Demirci, Deniz, Mutlu, Oguz, Akar, Furuzan, Celikyurt, Ipek Komsuoglu, Ulak, Guner
Fformat: Artigo
Iaith:Inglês
Cyhoeddwyd: International Scientific Literature, Inc. 2014
Pynciau:
Mynediad Ar-lein:https://ncbi.nlm.nih.gov/pmc/articles/PMC3936918/
https://ncbi.nlm.nih.gov/pubmed/24500039
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.12659/MSMBR.890280
Tagiau: Ychwanegu Tag
Dim Tagiau, Byddwch y cyntaf i dagio'r cofnod hwn!