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Differences between cotranscriptional and free riboswitch folding

Riboswitches are part of noncoding regions of messenger RNA (mRNA) that act as RNA sensors regulating gene expression of the downstream gene. Typically, one out of two distinct conformations is formed depending on ligand binding when the transcript leaves RNA polymerase (RNAP). Elongation of the RNA...

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Detalhes bibliográficos
Main Authors: Lutz, Benjamin, Faber, Michael, Verma, Abhinav, Klumpp, Stefan, Schug, Alexander
Formato: Artigo
Idioma:Inglês
Publicado em: Oxford University Press 2014
Assuntos:
RNA
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC3936736/
https://ncbi.nlm.nih.gov/pubmed/24275497
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1093/nar/gkt1213
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