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Huntingtin-associated protein (HAP1): discrete neuronal localizations in the brain resemble those of neuronal nitric oxide synthase.

Huntington disease stems from a mutation of the protein huntingtin and is characterized by selective loss of discrete neuronal populations in the brain. Despite a massive loss of neurons in the corpus striatum, NO-generating neurons are intact. We recently identified a brain-specific protein that as...

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Detalhes bibliográficos
Publicado no:Proc Natl Acad Sci U S A
Principais autores: Li, X J, Sharp, A H, Li, S H, Dawson, T M, Snyder, S H, Ross, C A
Formato: Artigo
Idioma:Inglês
Publicado em: National Academy of Sciences 1996
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.govhttps://pmc.ncbi.nlm.nih.gov/articles/PMC39366/
https://ncbi.nlm.nih.govhttps://pubmed.ncbi.nlm.nih.gov/8643490/
https://ncbi.nlm.nih.govhttps://doi.org/10.1073/pnas.93.10.4839
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