A-Ring Modified Betulinic Acid Derivatives as Potent Cancer Preventive Agents

Ten new 3,4-seco betulinic acid (BA) derivatives were designed and synthesized. Among them, compounds 7–15 exhibited enhanced chemopreventive ability in an in vitro short-term 12-O-tetradecanoylphorbol-13-acetate (TPA) induced Epstein-Barr virus early antigen (EBV-EA) activation assay in Raji cells....

Deskribapen osoa

Gorde:
Xehetasun bibliografikoak
Egile Nagusiak: Hung, Hsin-Yi, Nakagawa-Goto, Kyoko, Tokuda, Harukuni, Iida, Akira, Suzuki, Nobutaka, Bori, Ibrahim D., Qian, Keduo, Lee, Kuo-Hsiung
Formatua: Artigo
Hizkuntza:Inglês
Argitaratua: 2013
Gaiak:
Article
Sarrera elektronikoa:https://ncbi.nlm.nih.gov/pmc/articles/PMC3936349/
https://ncbi.nlm.nih.gov/pubmed/24411124
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.bmcl.2013.12.041
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