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Improved Vascular Survival and Growth in the Mouse Model of Hindlimb Ischemia by a Remote Signaling Mechanism

Deficiencies in prolyl hydroxylase domain proteins (PHDs) may lead to the accumulation of hypoxia-inducible factor-α proteins, the latter of which activate local angiogenic responses by paracrine mechanisms. Here, we investigate whether a keratinocyte-specific PHD deficiency may promote vascular sur...

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Main Authors: Takeda, Kotaro, Duan, Li-Juan, Takeda, Hiromi, Fong, Guo-Hua
Formato: Artigo
Idioma:Inglês
Publicado: American Society for Investigative Pathology 2014
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Acceso en liña:https://ncbi.nlm.nih.gov/pmc/articles/PMC3936330/
https://ncbi.nlm.nih.gov/pubmed/24440788
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.ajpath.2013.11.032
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