The role of KCNQ1 in mouse and human gastrointestinal cancers

Kcnq1, which encodes for the pore-forming alpha subunit of a voltage-gated potassium channel, was identified as a gastrointestinal (GI) tract cancer susceptibility gene in multiple Sleeping Beauty DNA transposon-based forward genetic screens in mice. To confirm that Kcnq1 has a functional role in GI...

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Main Authors: Than, B. L. N, Goos, J. A. C. M., Sarver, A. L., O’Sullivan, M. G., Rod, A., Starr, T. K., Fijneman, R. J. A., Meijer, G. A., Zhao, L, Zhang, Y, Largaespada, D. A., Scott, P. M., Cormier, R. T.
Format: Artigo
Sprog:Inglês
Udgivet: 2013
Fag:
Article
Online adgang:https://ncbi.nlm.nih.gov/pmc/articles/PMC3935979/
https://ncbi.nlm.nih.gov/pubmed/23975432
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/onc.2013.350
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