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CFTR Mutations Spectrum and the Efficiency of Molecular Diagnostics in Polish Cystic Fibrosis Patients

Cystic fibrosis (CF) is caused by mutations in the cystic fibrosis transmembrane regulator gene (CFTR). In light of the strong allelic heterogeneity and regional specificity of the mutation spectrum, the strategy of molecular diagnostics and counseling in CF requires genetic tests to reflect the fre...

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Detalhes bibliográficos
Main Authors: Ziętkiewicz, Ewa, Rutkiewicz, Ewa, Pogorzelski, Andrzej, Klimek, Barbara, Voelkel, Katarzyna, Witt, Michał
Formato: Artigo
Idioma:Inglês
Publicado em: Public Library of Science 2014
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC3935850/
https://ncbi.nlm.nih.gov/pubmed/24586523
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1371/journal.pone.0089094
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