Retinoic acid inducible gene-I (RIG-I) signaling of hepatic stellate cells inhibits hepatitis C virus replication in hepatocytes

Retinoic acid inducible gene-I (RIG-I) is critical in the activation of the type I IFN-dependent antiviral innate immune response to hepatitis C virus (HCV) infection. We examined whether hepatic stellate cells (HSC; LX-2) possess a functional RIG-I signaling pathway and produce antiviral factors th...

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Bibliographic Details
Main Authors: Wang, Yizhong, Ye, Li, Wang, Xu, Li, Jieliang, Song, Li, Ho, Wenzhe
Format: Artigo
Language:Inglês
Published: 2012
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Article
Online Access:https://ncbi.nlm.nih.gov/pmc/articles/PMC3935722/
https://ncbi.nlm.nih.gov/pubmed/23060457
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1177/1753425912460414
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