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Nuclear Localization Signals in Prototype Foamy Viral Integrase for Successive Infection and Replication in Dividing Cells

We identified four basic amino acid residues as nuclear localization signals (NLS) in the C-terminal domain of the prototype foamy viral (PFV) integrase (IN) protein that were essential for viral replication. We constructed seven point mutants in the C-terminal domain by changing the lysine and argi...

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Main Authors: Hossain, Alamgir, Ali, Khadem, Shin, Cha-Gyun
格式: Artigo
語言:Inglês
出版: Korea Society for Molecular and Cellular Biology 2014
在線閱讀:https://ncbi.nlm.nih.gov/pmc/articles/PMC3935627/
https://ncbi.nlm.nih.gov/pubmed/24598999
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.14348/molcells.2014.2331
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