Physiological implications of NTBI uptake by T lymphocytes

In iron overload disorders a significant fraction of the total iron circulates in the plasma as low molecular weight complexes not bound to transferrin, known as non-transferrin-bound iron (NTBI). By catalyzing the formation of free radicals, NTBI accumulation results in oxidative stress and cellula...

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Detalhes bibliográficos
Main Authors: Pinto, Jorge P., Arezes, João, Dias, Vera, Oliveira, Susana, Vieira, Inês, Costa, Mónica, Vos, Matthijn, Carlsson, Anna, Rikers, Yuri, Rangel, Maria, Porto, Graça
Formato: Artigo
Idioma:Inglês
Publicado em: Frontiers Media S.A. 2014
Assuntos:
Pharmacology
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC3935319/
https://ncbi.nlm.nih.gov/pubmed/24616700
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.3389/fphar.2014.00024
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