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DNA sequence changes in an upstream DNase I-hypersensitive region are correlated with reduced gene expression.

Previous experiments have identified a region that is required for the expression of the Drosophila glue protein gene Sgs-4 and is located 300-500 base pairs upstream from the structural gene. The chromatin in this region changes conformation and becomes hypersensitive to DNase I digestion when the...

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Bibliografski detalji
Glavni autori: McGinnis, W, Shermoen, A W, Heemskerk, J, Beckendorf, S K
Format: Artigo
Jezik:Inglês
Izdano: 1983
Teme:
Online pristup:https://ncbi.nlm.nih.gov/pmc/articles/PMC393528/
https://ncbi.nlm.nih.gov/pubmed/6405379
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