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Activation of Toll-Like Receptors Inhibits Herpes Simplex Virus-1 Infection of Human Neuronal Cells

Toll-like receptors (TLRs) play an essential role in initiating intracellular type I interferon (IFN)-mediated innate immunity against viral infections. We examined whether human neuronal cells (primary human neurons, NT2-N and CHP-212 cells) express TLRs and mount type I IFN-mediated innate immunit...

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Main Authors: Zhou, Yu, Ye, Li, Wan, Qi, Zhou, Lin, Wang, Xu, Li, Jieliang, Hu, Shuxian, Zhou, Dunjin, Ho, Wenzhe
Format: Artigo
Jezik:Inglês
Izdano: 2009
Teme:
Online dostop:https://ncbi.nlm.nih.gov/pmc/articles/PMC3935181/
https://ncbi.nlm.nih.gov/pubmed/19437550
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1002/jnr.22110
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