Receptor-mediated phosphorylation of the hepatic insulin receptor: Evidence that the M(r) 95,000 receptor subunit is its own kinase

Insulin stimulates the phosphorylation of its own receptor. In the work reported here, the kinase activity responsible for the insulin-stimulated phosphorylation of the insulin receptor was localized. In a first approach, partially purified insulin receptors derived from normal rat hepatocytes were...

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Publié dans:	Proc Natl Acad Sci U S A
Auteurs principaux:	Van Obberghen, Emmanuel, Rossi, Bernard, Kowalski, Aline, Gazzano, Helene, Ponzio, Gilles
Format:	Artigo
Langue:	Inglês
Publié:	National Academy of Sciences 1983
Sujets:	Biological Sciences: Biochemistry
Accès en ligne:	https://ncbi.nlm.nih.govhttps://pmc.ncbi.nlm.nih.gov/articles/PMC393504/ https://ncbi.nlm.nih.govhttps://pubmed.ncbi.nlm.nih.gov/6341991/ https://ncbi.nlm.nih.govhttps://doi.org/10.1073/pnas.80.4.945
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