Receptor-mediated phosphorylation of the hepatic insulin receptor: Evidence that the M(r) 95,000 receptor subunit is its own kinase

Insulin stimulates the phosphorylation of its own receptor. In the work reported here, the kinase activity responsible for the insulin-stimulated phosphorylation of the insulin receptor was localized. In a first approach, partially purified insulin receptors derived from normal rat hepatocytes were...

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Veröffentlicht in:	Proc Natl Acad Sci U S A
Hauptverfasser:	Van Obberghen, Emmanuel, Rossi, Bernard, Kowalski, Aline, Gazzano, Helene, Ponzio, Gilles
Format:	Artigo
Sprache:	Inglês
Veröffentlicht:	National Academy of Sciences 1983
Schlagworte:	Biological Sciences: Biochemistry
Online-Zugang:	https://ncbi.nlm.nih.govhttps://pmc.ncbi.nlm.nih.gov/articles/PMC393504/ https://ncbi.nlm.nih.govhttps://pubmed.ncbi.nlm.nih.gov/6341991/ https://ncbi.nlm.nih.govhttps://doi.org/10.1073/pnas.80.4.945
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