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Culture of Primary Ciliary Dyskinesia Epithelial Cells at Air-Liquid Interface Can Alter Ciliary Phenotype but Remains a Robust and Informative Diagnostic Aid

BACKGROUND: The diagnosis of primary ciliary dyskinesia (PCD) requires the analysis of ciliary function and ultrastructure. Diagnosis can be complicated by secondary effects on cilia such as damage during sampling, local inflammation or recent infection. To differentiate primary from secondary abnor...

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Bibliographic Details
Main Authors: Hirst, Robert A., Jackson, Claire L., Coles, Janice L., Williams, Gwyneth, Rutman, Andrew, Goggin, Patricia M., Adam, Elizabeth C., Page, Anthony, Evans, Hazel J., Lackie, Peter M., O’Callaghan, Christopher, Lucas, Jane S.
Format: Artigo
Language:Inglês
Published: Public Library of Science 2014
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Online Access:https://ncbi.nlm.nih.gov/pmc/articles/PMC3934921/
https://ncbi.nlm.nih.gov/pubmed/24586956
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1371/journal.pone.0089675
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