Assessing Interactions of Two Loci (rs4242382 and rs10486567) in Familial Prostate Cancer: Statistical Evaluation of Epistasis

Understanding the impact of multiple genetic variants and their interactions on the disease penetrance of familial multiple prostate cancer is very relevant to the overall understanding of carcinogenesis. We assessed the joint effect of two loci on rs4242382 at 8q24 and rs10486567 at 7p15.2 to this...

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Main Authors: Chen, Li-Sheng, Fann, Jean Ching-Yuan, Chiu, Sherry Yueh-Hsia, Yen, Amy Ming-Fang, Wahlfors, Tiina, Tammela, Teuvo L., Chen, Hsiu-Hsi, Auvinen, Anssi, Schleutker, Johanna
Format: Artigo
Sprog:Inglês
Udgivet: Public Library of Science 2014
Fag:
Research Article
Online adgang:https://ncbi.nlm.nih.gov/pmc/articles/PMC3934901/
https://ncbi.nlm.nih.gov/pubmed/24586834
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1371/journal.pone.0089508
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