Assessing Interactions of Two Loci (rs4242382 and rs10486567) in Familial Prostate Cancer: Statistical Evaluation of Epistasis

Understanding the impact of multiple genetic variants and their interactions on the disease penetrance of familial multiple prostate cancer is very relevant to the overall understanding of carcinogenesis. We assessed the joint effect of two loci on rs4242382 at 8q24 and rs10486567 at 7p15.2 to this...

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Detalhes bibliográficos
Main Authors: Chen, Li-Sheng, Fann, Jean Ching-Yuan, Chiu, Sherry Yueh-Hsia, Yen, Amy Ming-Fang, Wahlfors, Tiina, Tammela, Teuvo L., Chen, Hsiu-Hsi, Auvinen, Anssi, Schleutker, Johanna
Formato: Artigo
Idioma:Inglês
Publicado em: Public Library of Science 2014
Assuntos:
Research Article
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC3934901/
https://ncbi.nlm.nih.gov/pubmed/24586834
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1371/journal.pone.0089508
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