Clinical Validation of a PCR Assay for the Detection of EGFR Mutations in Non–Small-Cell Lung Cancer: Retrospective Testing of Specimens from the EURTAC Trial

The EURTAC trial demonstrated that the tyrosine kinase inhibitor (TKI) erlotinib was superior to chemotherapy as first-line therapy for advanced non-small cell lung cancers (NSCLC) that harbor EGFR activating mutations in a predominantly Caucasian population. Based on EURTAC and several Asian trials...

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Main Authors: Benlloch, Susana, Botero, Maria Luisa, Beltran-Alamillo, Jordi, Mayo, Clara, Gimenez-Capitán, Ana, de Aguirre, Itziar, Queralt, Cristina, Ramirez, Jose Luis, Cajal, Santiago Ramón y., Klughammer, Barbara, Schlegel, Mariette, Bordogna, Walter, Chen, David, Zhang, Guili, Kovach, Barbara, Shieh, Felice, Palma, John F., Wu, Lin, Lawrence, H. Jeffrey, Taron, Miquel
Formato: Artigo
Idioma:Inglês
Publicado em: Public Library of Science 2014
Assuntos:
Research Article
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC3934888/
https://ncbi.nlm.nih.gov/pubmed/24586842
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1371/journal.pone.0089518
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