A Functional Polymorphism in the Promoter Region of MicroRNA-146a Is Associated with the Risk of Alzheimer Disease and the Rate of Cognitive Decline in Patients

miR146a is well known for its regulatory role in the immune response and inflammation. Recent studies have demonstrated the links between miR146a and Alzheimer disease (AD) and suggested that miR146a may be involved in neuroinflammation and the metabolism of amyloid-β (Aβ), which are critical events...

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Main Authors: Cui, Lili, Li, You, Ma, Guoda, Wang, Yan, Cai, Yujie, Liu, Shengyuan, Chen, Yanyan, Li, Jia, Xie, Yuliu, Liu, Gen, Zhao, Bin, Li, Keshen
格式: Artigo
語言:Inglês
出版: Public Library of Science 2014
主題:
Research Article
在線閱讀:https://ncbi.nlm.nih.gov/pmc/articles/PMC3934871/
https://ncbi.nlm.nih.gov/pubmed/24586483
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1371/journal.pone.0089019
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