A Functional Polymorphism in the Promoter Region of MicroRNA-146a Is Associated with the Risk of Alzheimer Disease and the Rate of Cognitive Decline in Patients

miR146a is well known for its regulatory role in the immune response and inflammation. Recent studies have demonstrated the links between miR146a and Alzheimer disease (AD) and suggested that miR146a may be involved in neuroinflammation and the metabolism of amyloid-β (Aβ), which are critical events...

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Bibliographic Details
Main Authors: Cui, Lili, Li, You, Ma, Guoda, Wang, Yan, Cai, Yujie, Liu, Shengyuan, Chen, Yanyan, Li, Jia, Xie, Yuliu, Liu, Gen, Zhao, Bin, Li, Keshen
Format: Artigo
Language:Inglês
Published: Public Library of Science 2014
Subjects:
Research Article
Online Access:https://ncbi.nlm.nih.gov/pmc/articles/PMC3934871/
https://ncbi.nlm.nih.gov/pubmed/24586483
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1371/journal.pone.0089019
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