The effect of an advanced glycation end-product crosslink breaker and exercise training on vascular function in older individuals: a randomized factorial design trial

Aging leads to accumulation of irreversible advanced glycation end-products (AGEs), contributing to vascular stiffening and endothelial dysfunction. When combined with the AGE-crosslink breaker Alagebrium, exercise training reverses cardiovascular aging in experimental animals. This study is the fir...

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Autores principales: Oudegeest-Sander, Madelijn H., Rikkert, Marcel G.M. Olde, Smits, Paul, Thijssen, Dick H.J., van Dijk, Arie P.J., Levine, Benjamin D., Hopman, Maria T.E.
Formato: Artigo
Lenguaje:Inglês
Publicado: 2013
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Article
Acceso en línea:https://ncbi.nlm.nih.gov/pmc/articles/PMC3934851/
https://ncbi.nlm.nih.gov/pubmed/24400341
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.exger.2013.10.009
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