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How does β-adrenergic signalling affect the transitions from ventricular tachycardia to ventricular fibrillation?

AIMS: Ventricular tachycardia (VT) and fibrillation (VF) are the most lethal cardiac arrhythmias. The degeneration of VT into VF is associated with the breakup of a spiral wave of the action potential in cardiac tissue. β-Adrenergic (βAR) signalling potentiates the L-type Ca current (I(CaL)) faster...

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Autors principals: Xie, Yuanfang, Grandi, Eleonora, Bers, Donald M., Sato, Daisuke
Format: Artigo
Idioma:Inglês
Publicat: Oxford University Press 2014
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Accés en línia:https://ncbi.nlm.nih.gov/pmc/articles/PMC3934848/
https://ncbi.nlm.nih.gov/pubmed/24569900
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1093/europace/eut412
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