Honokiol Enhances Paclitaxel Efficacy in Multi-Drug Resistant Human Cancer Model through the Induction of Apoptosis

Resistance to chemotherapy remains a major obstacle in cancer therapy. This study aimed to evaluate the molecular mechanism and efficacy of honokiol in inducing apoptosis and enhancing paclitaxel chemotherapy in pre-clinical multi-drug resistant (MDR) cancer models, including lineage-derived human M...

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Bibliographic Details
Main Authors: Wang, Xu, Beitler, Jonathan J., Wang, Hong, Lee, Michael J., Huang, Wen, Koenig, Lydia, Nannapaneni, Sreenivas, Amin, A. R. M. Ruhul, Bonner, Michael, Shin, Hyung Ju C., Chen, Zhuo Georgia, Arbiser, Jack L., Shin, Dong M.
Format: Artigo
Language:Inglês
Published: Public Library of Science 2014
Subjects:
Research Article
Online Access:https://ncbi.nlm.nih.gov/pmc/articles/PMC3934844/
https://ncbi.nlm.nih.gov/pubmed/24586249
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1371/journal.pone.0086369
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