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Honokiol Enhances Paclitaxel Efficacy in Multi-Drug Resistant Human Cancer Model through the Induction of Apoptosis

Resistance to chemotherapy remains a major obstacle in cancer therapy. This study aimed to evaluate the molecular mechanism and efficacy of honokiol in inducing apoptosis and enhancing paclitaxel chemotherapy in pre-clinical multi-drug resistant (MDR) cancer models, including lineage-derived human M...

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Autors principals: Wang, Xu, Beitler, Jonathan J., Wang, Hong, Lee, Michael J., Huang, Wen, Koenig, Lydia, Nannapaneni, Sreenivas, Amin, A. R. M. Ruhul, Bonner, Michael, Shin, Hyung Ju C., Chen, Zhuo Georgia, Arbiser, Jack L., Shin, Dong M.
Format: Artigo
Idioma:Inglês
Publicat: Public Library of Science 2014
Matèries:
Accés en línia:https://ncbi.nlm.nih.gov/pmc/articles/PMC3934844/
https://ncbi.nlm.nih.gov/pubmed/24586249
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1371/journal.pone.0086369
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