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The Influence of Spatial Variation in Chromatin Density Determined by X-Ray Tomograms on the Time to Find DNA Binding Sites

In this work, we examine how volume exclusion caused by regions of high chromatin density might influence the time required for proteins to find specific DNA binding sites. The spatial variation of chromatin density within mouse olfactory sensory neurons is determined from soft X-ray tomography reco...

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Detalhes bibliográficos
Main Authors: Isaacson, Samuel A., Larabell, Carolyn A., Le Gros, Mark A., McQueen, David M., Peskin, Charles S.
Formato: Artigo
Idioma:Inglês
Publicado em: 2013
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC3934756/
https://ncbi.nlm.nih.gov/pubmed/23955281
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1007/s11538-013-9883-9
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