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The influence of volume exclusion by chromatin on the time required to find specific DNA binding sites by diffusion
Within the nuclei of eukaryotic cells, the density of chromatin is nonuniform. We study the influence of this nonuniform density, which we derive from microscopic images [Schermelleh L, et al. (2008) Science 320:1332–1336], on the diffusion of proteins within the nucleus, under the hypothesis that c...
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| Main Authors: | , , |
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| Formato: | Artigo |
| Idioma: | Inglês |
| Publicado: |
National Academy of Sciences
2011
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| Assuntos: | |
| Acceso en liña: | https://ncbi.nlm.nih.gov/pmc/articles/PMC3048119/ https://ncbi.nlm.nih.gov/pubmed/21300894 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1073/pnas.1018821108 |
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