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The influence of volume exclusion by chromatin on the time required to find specific DNA binding sites by diffusion

Within the nuclei of eukaryotic cells, the density of chromatin is nonuniform. We study the influence of this nonuniform density, which we derive from microscopic images [Schermelleh L, et al. (2008) Science 320:1332–1336], on the diffusion of proteins within the nucleus, under the hypothesis that c...

Deskribapen osoa

Gorde:
Xehetasun bibliografikoak
Egile Nagusiak: Isaacson, S. A., McQueen, D. M., Peskin, Charles S.
Formatua: Artigo
Hizkuntza:Inglês
Argitaratua: National Academy of Sciences 2011
Gaiak:
Sarrera elektronikoa:https://ncbi.nlm.nih.gov/pmc/articles/PMC3048119/
https://ncbi.nlm.nih.gov/pubmed/21300894
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1073/pnas.1018821108
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