Mechanisms by which a CACNA1H mutation in epilepsy patients increases seizure susceptibility

T-type calcium channels play essential roles in regulating neuronal excitability and network oscillations in the brain. Mutations in the gene encoding Ca(v)3.2 T-type Ca(2+) channels, CACNA1H, have been found in association with various forms of idiopathic generalized epilepsy. We and others have fo...

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Hlavní autoři: Eckle, Veit-Simon, Shcheglovitov, Aleksandr, Vitko, Iuliia, Dey, Deblina, Yap, Chan Choo, Winckler, Bettina, Perez-Reyes, Edward
Médium: Artigo
Jazyk:Inglês
Vydáno: Blackwell publishing Ltd 2014
Témata:
Neuroscience: Neurobiology of Disease
On-line přístup:https://ncbi.nlm.nih.gov/pmc/articles/PMC3934715/
https://ncbi.nlm.nih.gov/pubmed/24277868
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1113/jphysiol.2013.264176
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