The Phosphoinositide Kinase PIKfyve Mediates EGF Receptor Trafficking to the Nucleus

ErbB receptor tyrosine kinases can transit to nuclei in tumor cells, where they have been shown to regulate gene expression as components of transcriptional complexes. Quantitative analysis of a human bladder cancer tissue microarray identified nuclear EGFR in tumor cells and also showed an increase...

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Autori principali: Kim, Jayoung, Jahng, Wan Jin, Di Vizio, Dolores, Lee, Julie S., Jhaveri, Raj, Rubin, Mark A., Shisheva, Assia, Freeman, Michael R.
Natura: Artigo
Lingua:Inglês
Pubblicazione: 2007
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Article
Accesso online:https://ncbi.nlm.nih.gov/pmc/articles/PMC3934554/
https://ncbi.nlm.nih.gov/pubmed/17909029
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1158/0008-5472.CAN-07-1333
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