Hemojuvelin Modulates Iron Stress During Acute Kidney Injury: Improved by Furin Inhibitor

Aims: Free iron plays an important role in the pathogenesis of acute kidney injury (AKI) via the formation of hydroxyl radicals. Systemic iron homeostasis is controlled by the hemojuvelin-hepcidin-ferroportin axis in the liver, but less is known about this role in AKI. Results: By proteomics, we ide...

Ausführliche Beschreibung

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Bibliographische Detailangaben
Hauptverfasser: Young, Guang-Huar, Huang, Tao-Min, Wu, Che-Hsiung, Lai, Chun-Fu, Hou, Chun-Cheng, Peng, Kang-Yung, Liang, Chan-Jung, Lin, Shuei-Liong, Chang, Shih-Chung, Tsai, Pi-Ru, Wu, Kwan-Dun, Wu, Vin-Cent, Ko, Wen-Je
Format: Artigo
Sprache:Inglês
Veröffentlicht: Mary Ann Liebert, Inc. 2014
Schlagworte:
Original Research Communications
Online Zugang:https://ncbi.nlm.nih.gov/pmc/articles/PMC3934545/
https://ncbi.nlm.nih.gov/pubmed/23901875
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1089/ars.2013.5366
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