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Epigenome-wide differences in pathology-free regions of multiple sclerosis–affected brains

Using the Illumina 450K array and a stringent statistical analysis with age and gender correction, we report genome-wide differences in DNA methylation between pathology-free regions derived from human multiple sclerosis–affected and control brains. Differences were subtle, but widespread and reprod...

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Sonraí Bibleagrafaíochta
Main Authors: Huynh, Jimmy L, Garg, Paras, Thin, Tin Htwe, Yoo, Seungyeul, Dutta, Ranjan, Trapp, Bruce D, Haroutunian, Vahram, Zhu, Jun, Donovan, Michael J, Sharp, Andrew J, Casaccia, Patrizia
Formáid: Artigo
Teanga:Inglês
Foilsithe: 2013
Ábhair:
Rochtain Ar Líne:https://ncbi.nlm.nih.gov/pmc/articles/PMC3934491/
https://ncbi.nlm.nih.gov/pubmed/24270187
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/nn.3588
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