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Nicotinamide: a Class III HDACi Delays In Vitro Aging of Mouse Oocytes
Postovulatory mammalian oocyte developmental potential decreases with aging in vivo and in vitro. Aging oocytes typically show cellular fragmentation and chromosome scattering with an abnormally shaped spindle over time. Previously, it was shown that histone acetylation in the mouse oocyte increased...
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| Main Authors: | , , , , , |
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| Formato: | Artigo |
| Idioma: | Inglês |
| Publicado em: |
The Society for Reproduction and Development
2013
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| Assuntos: | |
| Acesso em linha: | https://ncbi.nlm.nih.gov/pmc/articles/PMC3934134/ https://ncbi.nlm.nih.gov/pubmed/23474603 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1262/jrd.2012-171 |
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