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Lgr4 regulates mammary gland development and stem cell activity through the pluripotency transcription factor Sox2

The key signaling networks regulating mammary stem cells are poorly defined. The leucine-rich repeat containing G-protein coupled receptor (Lgr) family has been implicated in intestinal, gastric, and epidermal stem cell functions. We investigated whether Lgr4 functions in mammary gland development a...

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Detalhes bibliográficos
Main Authors: Wang, Ying, Dong, Jie, Li, Dali, Lai, Li, Siwko, Stefan, Li, Yi, Liu, Mingyao
Formato: Artigo
Idioma:Inglês
Publicado em: 2013
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC3934111/
https://ncbi.nlm.nih.gov/pubmed/23712846
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1002/stem.1438
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