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p11 and its role in depression and therapeutic responses to antidepressants

Studies of the multifunctional protein p11 (also known as S100A10) are shedding light on the molecular and cellular mechanisms underlying depression. Here we review data implicating p11 in both the amplification of serotonergic signaling and the regulation of gene transcription. We summarize studies...

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Bibliographic Details
Main Authors: Svenningsson, Per, Kim, Yong, Warner-Schmidt, Jennifer, Oh, Yong-Seok, Greengard, Paul
Format: Artigo
Language:Inglês
Published: 2013
Subjects:
Online Access:https://ncbi.nlm.nih.gov/pmc/articles/PMC3933996/
https://ncbi.nlm.nih.gov/pubmed/24002251
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/nrn3564
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