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Evidence for a role of the 5-HT(1B) receptor and its adaptor protein, p11, in l-DOPA treatment of an animal model of Parkinsonism
Parkinson's disease (PD) is characterized by a progressive degeneration of substantia nigra dopaminergic neurons projecting to the striatum. Restoration of dopamine transmission by l-DOPA relieves symptoms of PD but causes prominent side effects. There is a strong serotonin innervation of the s...
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| Main Authors: | , , , |
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| Formato: | Artigo |
| Idioma: | Inglês |
| Publicado em: |
National Academy of Sciences
2008
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| Assuntos: | |
| Acesso em linha: | https://ncbi.nlm.nih.gov/pmc/articles/PMC2538893/ https://ncbi.nlm.nih.gov/pubmed/18256188 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1073/pnas.0711839105 |
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