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Lipoprotein Receptor–Related Protein-6 Protects the Brain From Ischemic Injury

BACKGROUND AND PURPOSE: Loss-of-function mutations of the lipoprotein receptor–related protein-6 (LRP6), a coreceptor in the Wingless-related integration site-β–catenin prosurvival pathway, have been implicated in myocardial ischemia and neurodegeneration. However, it remains to be established wheth...

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Detalhes bibliográficos
Main Authors: Abe, Takato, Zhou, Ping, Jackman, Katherine, Capone, Carmen, Casolla, Barbara, Hochrainer, Karin, Kahles, Timo, Ross, Margaret Elizabeth, Anrather, Josef, Iadecola, Costantino
Formato: Artigo
Idioma:Inglês
Publicado em: 2013
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Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC3933931/
https://ncbi.nlm.nih.gov/pubmed/23743975
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1161/STROKEAHA.113.001320
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