Progranulin Deficiency Promotes Post-Ischemic Blood–Brain Barrier Disruption

Loss-of-function mutations of progranulin (PGRN) have been linked to frontotemporal dementia, but little is known about the effects of PGRN deficiency on the brain in health and disease. PGRN has been implicated in neurovascular development, inflammation, and Wnt signaling, a pathway involved in the...

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Main Authors: Jackman, Katherine, Kahles, Timo, Lane, Diane, Garcia-Bonilla, Lidia, Abe, Takato, Capone, Carmen, Hochrainer, Karin, Voss, Henning, Zhou, Ping, Ding, Aihao, Anrather, Josef, Iadecola, Costantino
Formato: Artigo
Idioma:Inglês
Publicado: Society for Neuroscience 2013
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Articles
Acceso en liña:https://ncbi.nlm.nih.gov/pmc/articles/PMC3858627/
https://ncbi.nlm.nih.gov/pubmed/24336722
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1523/JNEUROSCI.4318-13.2013
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