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Discretized Gaussian mixture for genotyping of microsatellite loci containing homopolymer runs

Motivation: Inferring lengths of inherited microsatellite alleles with single base pair resolution from short sequence reads is challenging due to several sources of noise caused by the repetitive nature of microsatellites and the technologies used to generate raw sequence data. Results: We have dev...

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Autori principali: Tae, Hongseok, Kim, Dong-Yun, McCormick, John, Settlage, Robert E., Garner, Harold R.
Natura: Artigo
Lingua:Inglês
Pubblicazione: Oxford University Press 2014
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Accesso online:https://ncbi.nlm.nih.gov/pmc/articles/PMC3933874/
https://ncbi.nlm.nih.gov/pubmed/24135263
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1093/bioinformatics/btt595
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