CXCR4 Inhibition Ameliorates Severe Obliterative Pulmonary Hypertension and Accumulation of C-Kit(+) Cells in Rats

Successful curative treatment of severe pulmonary arterial hypertension with luminal obliteration will require a thorough understanding of the mechanism underlying the development and progression of pulmonary vascular lesions. But the cells that obliterate the pulmonary arterial lumen in severe pulm...

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Bibliographic Details
Main Authors: Farkas, Daniela, Kraskauskas, Donatas, Drake, Jennifer I., Alhussaini, Aysar A., Kraskauskiene, Vita, Bogaard, Harm J., Cool, Carlyne D., Voelkel, Norbert F., Farkas, Laszlo
Format: Artigo
Language:Inglês
Published: Public Library of Science 2014
Subjects:
Research Article
Online Access:https://ncbi.nlm.nih.gov/pmc/articles/PMC3933653/
https://ncbi.nlm.nih.gov/pubmed/24587052
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1371/journal.pone.0089810
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