Dietary Flavonoids Modulate CYP2C to Improve Drug Oral Bioavailability and Their Qualitative/Quantitative Structure–Activity Relationship

This study aims to improve the drug oral bioavailability by co-administration with flavonoid inhibitors of the CYP2C isozyme and to establish qualitative and quantitative (QSAR) structure–activity relationships (SAR) between flavonoids and CYP2C. A total of 40 naturally occurring flavonoids were scr...

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Bibliografiske detaljer
Main Authors: Wang, Hong-Jaan, Pao, Li-Heng, Hsiong, Cheng-Huei, Shih, Tung-Yuan, Lee, Meei-Shyuan, Hu, Oliver Yoa-Pu
Format: Artigo
Sprog:Inglês
Udgivet: Springer US 2014
Fag:
Research Article
Online adgang:https://ncbi.nlm.nih.gov/pmc/articles/PMC3933575/
https://ncbi.nlm.nih.gov/pubmed/24431079
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1208/s12248-013-9549-4
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