RAGE Controls Activation and Anti-Inflammatory Signalling of Protein C

AIMS: The receptor for advanced glycation endproducts, RAGE, is a multiligand receptor and NF-κB activator leading to perpetuation of inflammation. We investigated whether and how RAGE is involved in mediation of anti-inflammatory properties of protein C. METHODS AND RESULTS: We analyzed the effect...

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Detalhes bibliográficos
Main Authors: Braach, Natascha, Frommhold, David, Buschmann, Kirsten, Pflaum, Johanna, Koch, Lutz, Hudalla, Hannes, Staudacher, Kathrin, Wang, Hongjie, Isermann, Berend, Nawroth, Peter, Poeschl, Johannes
Formato: Artigo
Idioma:Inglês
Publicado em: Public Library of Science 2014
Assuntos:
Research Article
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC3933550/
https://ncbi.nlm.nih.gov/pubmed/24586767
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1371/journal.pone.0089422
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