Protein C Concentrate Controls Leukocyte Recruitment during Inflammation and Improves Survival during Endotoxemia after Efficient in Vivo Activation

Anti-inflammatory properties of protein C (PC) concentrate are poorly studied compared to activated protein C, although PC is suggested to be safer in clinical use. We investigated how PC interferes with the leukocyte recruitment cascade during acute inflammation and its efficacy during murine endot...

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Hauptverfasser: Frommhold, David, Tschada, Julia, Braach, Natascha, Buschmann, Kirsten, Doerner, Axel, Pflaum, Johanna, Stahl, Marie-Sophie, Wang, Hongjie, Koch, Lutz, Sperandio, Markus, Bierhaus, Angelika, Isermann, Berend, Poeschl, Johannes
Format: Artigo
Sprache:Inglês
Veröffentlicht: American Society for Investigative Pathology 2011
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Regular Article
Online Zugang:https://ncbi.nlm.nih.gov/pmc/articles/PMC3204097/
https://ncbi.nlm.nih.gov/pubmed/21907691
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.ajpath.2011.07.023
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