Protein C Concentrate Controls Leukocyte Recruitment during Inflammation and Improves Survival during Endotoxemia after Efficient in Vivo Activation

Anti-inflammatory properties of protein C (PC) concentrate are poorly studied compared to activated protein C, although PC is suggested to be safer in clinical use. We investigated how PC interferes with the leukocyte recruitment cascade during acute inflammation and its efficacy during murine endot...

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Detalhes bibliográficos
Main Authors: Frommhold, David, Tschada, Julia, Braach, Natascha, Buschmann, Kirsten, Doerner, Axel, Pflaum, Johanna, Stahl, Marie-Sophie, Wang, Hongjie, Koch, Lutz, Sperandio, Markus, Bierhaus, Angelika, Isermann, Berend, Poeschl, Johannes
Formato: Artigo
Idioma:Inglês
Publicado em: American Society for Investigative Pathology 2011
Assuntos:
Regular Article
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC3204097/
https://ncbi.nlm.nih.gov/pubmed/21907691
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.ajpath.2011.07.023
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