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Multiwell stiffness assay for the study of cell responsiveness to cytotoxic drugs

It is now well understood that the cell microenvironment, including the surrounding matrix, profoundly affects cell fate. This is especially true for solid tumors where, for example, matrix stiffness is believed to be an important factor in tumorogenesis. Our hypothesis is that since matrix stiffnes...

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Bibliographic Details
Main Authors: Zustiak, Silviya, Nossal, Ralph, Sackett, Dan L.
Format: Artigo
Language:Inglês
Published: 2013
Subjects:
Online Access:https://ncbi.nlm.nih.gov/pmc/articles/PMC3933463/
https://ncbi.nlm.nih.gov/pubmed/24018833
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1002/bit.25097
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